Cashmere Wright led Cincinnatti with 22 points and singlehandedly kept the Bearcats in front in the first half with four three pointers in the first 10 minutes of play.
Cincinnati has now won two consecutive games over two teams heading into the NCAA Tournament and strengthen their at large case heading into the last week of play.
Louisville cut the lead to 56-53 on Siva's jumper but that was as close as they would get in the final 1:17.
Kyle Kuric who had been averaging 13 points per game had His worst shooting night as He shot 0-7 from beyond the arc and only scored 4 points for the game.
Chane Behanan had 11 points and 7 rebounds, Dieng had 11 points to go with 13 boards,Russ Smith's 11 and Peyton Siva's 14 and 4 assist led the Cards attack.
Cincinnati's three point shooting proved to be the difference in this contest last night as they shot .407 pct from the Arc on 11-27 shooting with Cashemere Wright hitting 6 of them.